9-13 November 2015, SPIRIT Summer School "Multimodal Molecular Imaging: from high resolution in vitro towards in vivo imaging" in Göttingen, Germany. On Thursday 12 November, Tagworks CEO Marc Robillard will instruct on 'Click Chemistry'.
Tagworks' ceo Marc Robillard will present Tagworks' technology at the Spring symposium of the French Society for Medicinal Chemistry on 'Bioorthogonal Chemistry contributing to Molecular Therapeutic Innovation' in Paris.
The latest edition of Medicines, a Dutch journal on drug development, features Tagworks Pharmaceuticals in the start-up sections. The article by Rik Nijland appeared in Medicines 1, February 2015 (in Dutch) 24_25_med1_startup
Developing an antibody tag with improved pharmacokinetics and stability allowed Tagworks to achieve increased tumor uptake of a radiolabeled pretargeting probe. Even though this adapted tag exhibited a slight loss in reactivity, its use in a antibody (CC49-TCO) conjugate demonstrated a longer clearance half-life, improved tumor accumulation and increased in …
Approaches that use in vivo chemistry to enable non-invasive molecular imaging and therapy are much sought after. Taking the recent achievements in pretargeted radioimmuno-imaging and -therapy in mice as a starting point, the Tagworks team discuss how the application scope of this approach can eventually be extended towards humans. Read …