Head of Protein Development

Headquartered in Nijmegen, The Netherlands, Tagworks Pharmaceuticals is a dynamic biotech company with strong backing from prominent US and European investors. Specializing in proprietary in vivo click chemistry, Tagworks is committed to improving the effectiveness and reducing the toxicity of systemic cancer treatments. Operating at the Radboud University Medical Center, Tagworks pioneers unique approaches towards antibody-drug conjugates, prodrugs, and targeted radiotherapeutics through its "Click-to-Release'' platform, rooted in Nobel Prize-winning research. To further strengthen the organization, we are looking for a Head of Protein Development.

The position
Our Head of Protein Development is responsible for leading the discovery, design, engineering and development activities of proteins, including antibody fragments and derivatives. Your work covers format research, protein design, bioinformatics, cloning & expression, screening and characterization. Together with the research teams you drive the development of proteins that are optimized for our pipeline of click-cleavable ADCs and other prodrugs. You collaborate with SME’s on protein modeling and engineering and oversee outsourced protein R&D at CROs.

The requirements

  • 10+ years experience in protein discovery, design and engineering in a biotech/pharmaceutical environment
  • PhD in Bioengineering, Biochemistry or a related field and a good understanding of molecular biology and the state of the art in discovery, design, screening, and development of proteins, ideally antibody fragments and derivatives
  • Sufficient experience in computational biology, bioinformatics and data mining to support protein development strategies
  • Strategic and innovative thinker with track record of developing creative approaches to tumor targeting and implementation of new technologies
  • Demonstrated ability to determine strategic priorities, set goals, and manage resources effectively
  • Experience in identifying and evaluating business development opportunities in tumor targeting is favorable
  • Experience in integrating and managing CROs to achieve project goals highly desirable
  • Skilled at clearly communicating strategy, recommendations, and priorities
  • Collaborates and works successfully with multiple key stakeholders and project teams

The offer
You will join a group of passionate and very skilled professionals working towards a common goal. We offer a set of attractive and competitive benefits, recognizing and rewarding our talented and motivated employees.

Our culture and values
At Tagworks, our culture is built on innovation, collaboration, inclusivity and achieving results. We prioritize teamwork, flexibility, resilience, adaptability, and fulfilling commitments.

How to apply
Please send your CV together with a cover letter to

Curious about what we do? Get in touch!


About    Our Technology   Pipeline    Join us    News    Contact

T +31 85 800 8550

Tagworks Pharmaceuticals BV
Toernooiveld 1
6525 ED  Nijmegen
The Netherlands

Stay updated

© Tagworks Pharmaceuticals, 2024 | Terms of use | Design by Ape to Zebra