Written by: Rick Jongerius

Tagworks Pharmaceuticals Announces FDA Clearance of IND Application and Initiation of Phase 1 Clinical Trial for TGW101 and Appoints Keith Orford, MD, PhD, as Chief Medical Officer 

Tagworks initiates Phase 1 trial for TGW101, a first-in-class Click-to-Release ADC targeting TAG-72, and appoints Dr. Keith Orford as Chief Medical Officer.
April 22, 2025

Tagworks Pharmaceuticals Announces Poster Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2025

Tagworks to present preclinical data demonstrating potential of its Click-to-Release platform to enable safe, tolerable, and potent delivery of therapeutic candidates for solid tumors
March 25, 2025

Tagworks Pharmaceuticals Appoints Ken Mills as Chief Executive Officer

Biotech industry veteran to lead Tagworks as the company prepares to bring its novel platform and lead antibody-drug conjugate (ADC) program for solid tumors into the clinic in 2025
October 1, 2024

Tagworks appoints Krisztina Nemenyi as Vice President Regulatory Affairs

We are excited to announce a recent addition to our rapidly expanding team: Krisztina Nemenyi has joined as our Vice President Regulatory Affairs.
September 9, 2024

Tagworks lands $65M for its take on Nobel-winning click chemistry in bid to expand ADC, radiopharma potential

A Dutch-American biotech is out with $65 million in Series A funding to get into the clinic with what it calls an expanded scope of the popular antibody-drug conjugates class after a decade of legwork iterating on the original click chemistry findings that led to last year’s Nobel Prize.
June 22, 2023

Tagworks’ click-to-release ADC approach draws $65M in series A round

By BioWorld Twelve years on from spinning out of Philips Healthcare, Tagworks Pharmaceuticals BV has raised $65 million in a series A round to take a new generation of antibody-drug conjugates (ADCs) based on click chemistry into the clinic. Read more.
June 22, 2023

Tagworks: using click chemistry to make ADCs more applicable and radiotherapies safer

By BioCentury Netherlands-based Tagworks is using click chemistry to simultaneously accomplish on-target activation of ADCs and off-target deactivation of radiopharmaceuticals. After spinning out of Philips Healthcare in 2011, the company has announced a $65 million series A round co-led by Ysios Capital and Gilde Healthcare. Download the complete article here.
June 22, 2023

Tagworks Pharmaceuticals Announces $65 Million in Series A Financing to Advance Click-to-Release Therapeutics

Financing round led by Ysios Capital and Gilde Healthcare with participation from Novartis Venture Fund, New Enterprise Associates, and Lightstone Ventures Unique Click-to-Release platform enables on-target activation of antibody-drug conjugates (ADCs) and immunomodulators, as well as off-target deactivation of radiopharmaceuticals Proceeds will be used to advance the lead program, a …
June 22, 2023

Click and bioorthogonal chemistry win 2022 Nobel Prize in Chemistry

Carolyn R. Bertozzi, Morten Meldal, and K. Barry Sharpless receive prize for their work on reactions that quickly link molecules and the application of the reactions in living cells Three scientists have won the 2022 Nobel Prize in Chemistry: Carolyn R. Bertozzi of Stanford University, Morten Meldal of the University …
October 5, 2022

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